A vaccine designed to protect against three different deadly coronaviruses shows success in mouse studies, demonstrating the viability of a pan-coronavirus vaccine developed by researchers at the Duke Human Vaccine Institute.
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In laboratory and primate tests, a new pan-coronavirus vaccine developed by the Duke Human Vaccine Institute has demonstrated wide protection against SARS-CoV-2 viruses and variants,
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Researchers at Duke have published new work in a scientific journal, showing that a potential HIV vaccine component proves effective in primate study.
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The National Institute of Allergy and Infectious Diseases awarded researchers at the Duke Human Vaccine Institute a contract that enables it to compete for projects advancing investigational vaccines to production for use in early clinical trials.
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UNC-Chapel Hill and Duke identify an antibody that blocks infections and minimizes symptoms against a broad array of coronaviruses.
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Duke investigators demonstrated in mice and monkeys that human antibodies lacked the ability to make SARS-CoV-2 infection worse and, instead, exerted their defensive powers against the infection. The findings help reinforce evidence that antibodies are safe when given as treatments or induced by COVID-19 vaccines.
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With $814,714 in initial federal funding, RTI International and Duke University’s Human Vaccine Institute will collaborate in a global project to identify viruses and other pathogens in wildlife that could cause disease in people, such as the coronavirus responsible for the COVID-19 pandemic.
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In the quest to develop an effective HIV vaccine, researchers have focused attention on identifying and targeting the region of the virus’s outer envelope where a lineage of antibodies are able to dock and neutralize the virus. That focus may change due to research at Duke University.
Read MoreResearchers at the Duke Human Vaccine Institute have led an effort to develop a more accurate way to gauge the incidence of HIV infections in large populations, which will improve research and prevention strategies worldwide.
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