UNC researchers continue to seek strategy for starving brain tumors
In an effort to starve brain cancer cells and put the brakes on tumor development, University of North Carolina Lineberger Comprehensive Cancer Center researchers blocked the main pathway that brain tumor cells use to convert sugar into energy. They hoped this would starve tumor cells and slow their growth. To their surprise, however, the strategy actually accelerated growth in laboratory models of medulloblastoma. Published in the journal Cancer Research, the study was part of a series of attempts by UNC Lineberger researchers to shut down the energy production machinery in medulloblastoma, the most common malignant brain tumor in children....
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