A roundup of the latest high-tech news “Hot Off the Wire” from The Associated Press and Local Tech Wire:

Jury orders Apple to pay $625.5M in patent suit

A jury in Texas has ordered Apple to pay $625.5 million for violating patents owned by a firm founded by a computer science professor.

Apple Inc. is challenging Friday’s verdict from the federal court in Tyler, Texas, saying the court has not yet looked at some of its counterclaims.

If upheld, the verdict would be one of the largest in a patent suit. The plaintiff is Mirror Worlds, a company founded by David Gelernter of Yale University to commercialize his ideas.

The patents cover characteristic Mac features such as Cover Flow, which lets the users skim through album covers or other content as if they were leaves in a book. Another is Time Machine, which performs automatic backups.

Microsoft strategy head to speak at Duke

The executive responsible for Microsoft’s long-term technology strategy is telling Duke University business students about how computers are learning to understand us better.

Craig Mundie is speaking Tuesday to students at Duke University’s Fuqua School of Business about technology trends that are transforming how humans interact with computers.

He was expected to talk about how advances in processors and software allow humans to become more involved with experiences playing out on wall-sized displays. Mobile devices already are adding features that respond to voice, touch and gestures.

Mundie also serves on President Obama’s Council of Advisors on Science and Technology.

NC foundation gifts $20M for cancer institute

A Charlotte-based foundation is announcing a gift of $20 million to create a cancer institute that will bring higher levels of care to communities across North and South Carolina.

The Charlotte Observer reported that the Leon Levine Foundation said the gift to Carolinas HealthCare System will create the Levine Cancer Institute.

The institute will expand access to cancer specialists, treatment, research and support services for patients served by 32 hospitals owned or managed by Carolinas HealthCare.

Many of the hospitals already offer treatment for cancer patients, but only the larger ones enroll patients in clinical trials that compare new drugs and other therapies to standard treatments.

Through the institute, clinical trials will be available to patients in smaller communities in the hospital network.

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