As many as 250 investors from around the U.S. will gather in the Bull City over the next two days for what is being touted as the largest event in the 24-year history of the Council for Entrepreneurial Development venture capital conference.

More than 60 companies, from the earliest startups selected to participate in “speed dating” meetings with potential backers to established firms being showcased as examples of venture done right, will participate in the two-day program.

The CED expanded its reach and appeal, bringing in companies from across the Southeast and from Pennsylvania. As a result, a crowd of 750 is expected to jam the Washington Duke Inn & Golf Club.

“The range of states that will be represented by investors is a surprise to me,” said CED President Monica Doss, noting that more than 20 will be represented. Among the pre-registered attendees are venture capitalists from as far away as California, Washington and Arizona to New York – and 12 from Massachusetts.

“It’s a landmark year since we opened the event up to the region and in doing so positioned the Triangle as the center of entrepreneurial gravity in the Southeast and Mid-Atlantic,” she added.

What Doss described as an “aggressive” recruiting team representing the CED scoured neighboring states for companies to make presentations. While the greatest number comes from North Carolina (32), Pennsylvania is represented by two firms, Georgia by seven, Florida by three, South Carolina by three and Maryland by one. That breakdown doesn’t include the 13 firms picked for the “speed dating” event, a new feature added for the conference.

The conference has been broken into two tracks – life sciences and technology.
Representatives from a wide variety of investment firms are already registered to attend. They include:

• Accuitive Medical Ventures

• Adena Ventures

• AdvaN.C.ed Technology Ventures

• AlliaN.C.e Technology Ventures L.P.

• Antares Capital Corporation

• Arcapita Ventures

• Ascent Venture Partners

• Aurora Funds

• Ballast Point Venture Partners

• BASF Venture Capital America

• Battery Ventures

• Boston Financial & Equity Corporation

• Burrill & Company

• Calvert Research Institute

• Canaan Partners

• Chrysalis Ventures

• CNF Investments

• Compass Capital

• Contender Capital

• Core Capital Partners

• Court Square Ventures

• Crossbow Ventures

• Delta Capital Management, LLC

• Dogwood Equity

• Edison Venture Fund

• Fletcher Spaght Ventures

• Frontier Capital, LLC

• Fulcrum Venture Partners

• Globespan Capital Partners

• Goldman Sachs

• Grotech Capital Group

• Harbert Venture Partners

• Harbor Island Equity Partners LLC

• Hatteras Venture Partners

• H.I.G. Ventures

• In-Q-Tel

• Intel Capital

• Intersouth Partners

• Johnson & Johnson Development Corporation

• Leader Ventures

• Massey Burch Capital Corp.

• Mid-Atlantic Venture Funds

• New Enterprise Associates

• New World Ventures

• N.C. IDEA

• Noro-Moseley Partners

• Novak Biddle Venture Partners

• Osage Ventures

• Oxford Bioscience Partners

• Oxford Finance Corporation

• Pappas Ventures

• Parish Capital Advisors

• Petra Capital

• Piedmont Angel Network

• Quaker BioVentures

• RCT BioVentures

• River Cities Capital Funds

• RiverVest Venture Partners

• Sigma Partners

• SJF Ventures

• Southern Capitol Ventures

• Spring Capital Partners, LP

• SSM Partners

• SunBridge Partners

• Tall Oaks Capital Partners LLC

• Technomark Group USA

• Telecommunications Development Fund

• Tobin Solitario Investment Banking Group

• Triarch Partners

• Triangle Accredited Capital Forum

• Updata Partners

• Wakefield Group

• Westlake Ventures

Showcase presentation companies include:

• ChannelAdvisor Corporation (Morrisville, N.C. – www.channeladvisor.com) ChannelAdvisor provides online channel management software and services.

• Innerpulse (RTP, N.C. – www.inner-pulse.com) InnerPulse is developing unique technologies for the treatment of abnormal heart rhythms.

• SkyCross (Viera, Fla. – www.skycross.com) SkyCross designs, develops and manufactures next-generation RF and antenna technology for mobile devices.

• Tengion (East Norriton, Pa., www.tengion.com) Tengion is developing new human tissues and organs that are derived from a patient’s own cells. Dr. Tony Atala, director of Wake Forest University’s Institute for Regenerative Medicine, is Tengion’s scientific founder.
Main Stage presenting companies are:

• Advanced Liquid Logic (RTP, N.C. – www.liquid-logic.com) Advanced Liquid Logic has developed a nanoliter lab-on-a-chip powered by digital microfluidics.

• AxoGen (Alachua, Fla. – www.axogeniNC.com) AxoGen provides surgeons with a biological solution to repair and regenerate peripheral nerves.

• Broadwick Corporation (Durham, N.C. – www.broadwick.com) Broadwick develops online communication software.

• CeNeRx BioPharma (Cary, N.C. – www.cenerx.com) CeNeRx is a pharmaceutical development company focused on identifying and developing promising therapeutics to treat diseases related to neurotransmitters.

• INI Power Systems (Morrisville, N.C. – www.inipower.com) INI Power Systems develops micro-fuel cells for portable power solutions.

• JackBe (Chevy Chase, Md. – www.jackbe.com) JackBe provides software and services for enterprise Web 2.0 business applications.

• Jacket Micro Devices (Atlanta – www.jacketmicro.com) Jacket Micro Devices provides RF modules for WLAN and WIMAX products.

• HyperBranch Medical Technology (Durham, N.C. – www.hyperbranch.com) HyperBranch Medical Technology develops, manufactures and distributes surgical sealants.

• Metabolon (Durham, N.C. – www.metabolon.com) Metabolon is a biomarker discovery and diagnostics company using metabolomics.

• Metastatix (Atlanta – www.metastatix.com) Metatstatix is a biopharmaceutical company developing small-molecule drugs to treat caN.C.er and HIV.

• Near-Time (Chapel Hill, N.C. – www.near-time.com) Near-Time develops Web 2.0 collaborative systems.

• N.C.ontact Surgical (Morrisville, N.C. – www.NContact.us) NContact is a medical device company that developed a cardiac coagulation device for the treatment of arrhythmias of the heart.

• Neotropix (Malvern, Pa.) Drug development using natural virus products for cancer.

• NovaMin Technology (Alachua, Fla. – www.novamin.com) NovaMin Technology has developed a new active ingredient for oral care products.

• Scentric (Alpharetta, Ga. – www.scentric.com) Scentric provides universal data classification solutions.

• TapRoot Systems (Morrisville, N.C. – www.taprootsystems.com) TapRoot Systems provides embedded software products and system integration services for the global mobile phone marketplace.

• Unitrends (Columbia, S.C. – www.unitrends.com) Unitrends is developing a complete system enabling on/off-site recovery of files, systems and data.

• ViTrue (Atlanta – www.vitrue.com) ViTrue has developed a user-created advertising platform.

Early Stage presenting firms include:

• Addrenex Pharmaceuticals (Durham, N.C.) Addrenex is a specialty pharmaceuticals company focused on developing and marketing drugs for adrenergic regulation.

• Adlyfe (Rockville, Md. – www.adlyfe.com) Adlyfe is a medical diagnostics company focused on bringing blood diagnostic products to the market for fatal brain diseases.

• Advanced Detection Technology (Clemmons, N.C. – www.detecttech.com) Advanced Detection Technology is a provider of physical security access control solutions.

• Cognosci(RTP, N.C. – www.cognosci.com) Cognosci is a pharmaceutical discovery and development company focused on creating novel compounds with anti-inflammatory and neuroprotective activity.

• CPS Biofuels IN.C.. (Cary, N.C. – www.cpsbiofuels.com) CPS Biofuels is focused on the development of proprietary processes to optimize biofuel alternatives.

• Digitalsmiths (Beaufort, S.C. – www.digitalsmiths.com) Digitalsmiths is a video search company providing solutions for advertising, user generated content and other consumer opportunities.

• ImagineOptix (Cary, N.C. – www.imagineoptix.com) ImagineOptix is developing portable video projection devices.

• InnerOptic Technology (Chapel Hill, N.C. – www.inneroptic.com) InnerOptic is a provider of advanced visualization systems for endoscopic surgery.

• Jenken Biosciences (RTP, N.C. – www.jenkenbio.com) Jenken is a clinical stage specialty pharmaceutical company focusing on repurposing approved drugs.

• Market Vue Partners (Durham, N.C. – www.mvue.com) Market Vue Partners provides database merchandising and database marketing services for the retail industry.

• Merscom (Chapel Hill, N.C. – www.merscom.com) Merscom is a publisher of casual games that compete on consumer analytics.

• Oncoscope (Chapel Hill, N.C.) Oncoscope plans to produce a novel optical biopsy system for detecting pre-cancerous cells.

• QSpex Technologies (Alpharetta, Ga. – www.qspex.com) QSpex is a medical device company working on proprietary ophthalmic lens production in eye care professionals’ offices.

• TeraDisc (Wilmington, N.C. – www.teradisc.org) TeraDisc is delivering high-performance computing applications for drug discovery.

• TheraSim (Durham, N.C. – www.therasim.com) TheraSim is developing medical software for measuring and improving clinical quality.

• Thermo Perfusion Systems (Decatur, Ga. – www.thermoperfusion.com) Thermo Perfusion Systems is a manufacturer of medical devices for site specific chemotherapy delivery.

• Whack.Net (Atlanta) Whack.Net is developing an online game competition portal.

• Zipit (Greenville, S.C. – www.zipitwireless.com) Zipit Wireless has developed a portable WiFi instant messaging products for tweens.

• ZyCare(Chapel Hill, N.C. – www.zycare.com) ZyCare is developing medical software for remote management of chronic disease.

Angel Investor Retreat Presenters include:

• Arbor Pharmaceuticals (Raleigh, N.C. – www.arborpharma.com) Arbor Pharmaceuticals licenses, develops and commercializes patented, late stage prescription pharmaceutical brands for significant pediatric conditions.

• Clinipace(Chapel Hill, N.C. – www.clinipace.com) Clinipace is a clinical research software company providing a single, integrated data capture and study management platform for post-approval research and registries.

• ContactAtOnce! (Roswell, Ga. – www.contactatoN.C.e.com) ContactAtOnce! is a Web-based communications service that humanizes businesses and connects them with prospective customers who are doing online research ahead of a big purchase.

• Dental Air Solutions (Holly Springs, N.C. – www.dentalairsolutions.com) Dental Air Solutions develops, markets and sells innovative devices in the dental equipment industry.

• Source Horizon (Greensboro, N.C. – www.sourceauthority.com) Source Horizon has developed the SourceAuthority.com marketplace to offer a full range of procurement services for manufacturers to acquire engineered components.

• Southeast TechInventures (Morrisville, N.C. – www.southeasttechinventures.com) Southeast TechInventures is a technology accelerator focused on developing and transitioning technologies from university labs to the commercial marketplace.

• SQL Sentry (Huntersville, N.C. – www.sqlsentry.com) SQL Sentry is an enterprise software company that delivers software tools for managing database servers and related IT resources for large and mid-size enterprises.

• Virtual Heroes (Cary, N.C. – www.virtualheroes.com) Virtual Heroes creates collaborative interactive learning solutions for the Federal Systems, Healthcare and Commercial markets.

• Zenph Studios (Raleigh, N.C. – www.zenph.com) Zenph Studios is an entertainment technology company developing audio applications for music production.