Three companies from Charlotte, another from Durham and one from South Carolina have made the finals of the Five Ventures business plan competition at the University of North Carolina at Charlotte.

The event is put on by the Charlotte Research Institute and UNC Charlotte.

The final round of competition is set for April 12 at the UNC Charlotte campus.

The finalists are:

• Accunetix (Durham): Created an affordable, highly sensitive molecular diagnostic technology that is relevant for a wide range of health-care applications, including testing for infectious diseases (HIV, HCV, HBV, TB, malaria) and cancer.

• A-Metrics LLC (Charlotte): Developed a new sensor technology that utilizes a patented method to track slight changes in pressure, temperature, humidity and the ability to record vibration frequencies in the sonar, seismic, and vocal ranges. Current applications include a more reliable detection of breast cancer, increased sensitivity of sonar devices, voice recognition and corrosive pipelines.

• HepatoSys Inc (Charlotte): Restores the function of donor livers for use in transplantation and evaluates the integrity of donor livers prior to initiation of the recipient operation.

• Kiyatec (Greenville, S.C.): Reduces the time and cost associated with pre-clinical drug discovery by developing and commercializing diagnostics that improve the correlation between lab-based results and clinical patient response.

• SellItAtSchool (Charlotte): is a Web site that empowers students, faculty and staff to resell supplies such as textbooks, study guides and equipment.