Regado Biosciences is looking to raise $80 million or more in its IPO. And it says a number of investors are already willing to buy close to $30 million in shares.

In an updated filing with the SEC, Regado priced its shares at between $14 and $16 each.

The company plans to offer 5 million shares.

Underwriters would have the option of purchasing another 750,000 shares.

“Certain of our existing stockholders, including stockholders affiliated with certain of our directors, have indicated an interest in purchasing up to an aggregate of approximately $29.5 million in shares of our common stock in this offering at the initial public offering price,” Regado said in the filing.

“However, because indications of interest are not binding agreements or commitments to purchase, the underwriters could determine to sell more, less or no shares to any of these potential investors and any of these potential investors could determine to purchase more, less or no shares in this offering.”

The company, which is seeking to commercialize technology developed at Duke University, has raised more than $110 million in financing dating back to 2005.

If the IPO is executed, Regado would trade on the Nasdaq under the symbol RGDO.

Cowen and Company, BMO Capital Markets, Canaccord Genuity, Needham & Company and Wedbush PacGrow Life Sciences are working with Regado as underwriters.

Funds will be used to develop one treatment in a Phase 3 clinical trial called REG1.

Noting that it is an “emerging” company, Regado is not disclosing all information typically supplied in an IPO filing.

“We are an ’emerging growth company’ as that term is used in the Jumpstart Our Business Startups Act of 2012 and, as such, have elected to comply with certain reduced public company reporting requirements for this prospectus and future filings,” the company said.

Regado raised $51 million in new financing, including backing from Triangle-based Aurora Funds, last December. The company closed on a “D” round of financing totaling just over $21.5 million in July of 2011. Regado has been raising the latest funding since December 2009.

Regado is based in New Jersey but maintains its research and development lab in Durham.

The firm landed a new investor in December, RusnanoMedInvest, which is part of a Russian government-owned investment firm called Rusnano.

Other investors included Baxter Ventures, which also is a new investor, along with previous backers Edmond de Rothschild Investment Partners, Domain Associates, Quaker Partners, Aurora and Caxton Advantage Life Sciences Fund.